SS31 (40mg) Injectable

Enhanced Mitochondrial Function: SS-31 improves bioenergetics by increasing ATP production, which is essential for cellular repair and energy-demanding processes. It is particularly beneficial in conditions like ischemia, where ATP recovery and mitochondrial efficiency are crucial for survival and recovery.

Muscle Protection in Cachexia: It shows potential in combating muscle wasting associated with cancer, chronic diseases, and chemotherapy. SS-31 improves muscle energy status, reduces catabolism, and protects against mitochondrial alterations, promoting muscle mass retention and physical endurance.

Cognitive Function: SS-31 improves memory and synaptic function by enhancing synaptic integrity and reducing neuroinflammation, making it a potential treatment for neurodegenerative diseases.

Reduced Oxidative Stress: By decreasing the production of reactive oxygen species (ROS), SS-31 stabilizes mitochondrial membranes, protecting tissues like the heart, skeletal muscle, and kidneys from oxidative damage.

Cardiovascular and Ocular Health: It has been shown to improve cardiovascular function and enhance visual function in age-related macular degeneration, especially improving low-luminance vision, which can enhance quality of life for patients with impaired vision.

Active Cancer: SS-31 may enhance cellular metabolism and energy production, so it should be used cautiously in patients with active cancer unless prescribed by a healthcare provider.

Pregnant or Breastfeeding Women: The safety of SS-31 during pregnancy or breastfeeding is not established; therefore, it is not recommended for these populations.

Age-Related Diseases: SS-31 supports conditions like heart failure, age-related macular degeneration, and chronic kidney disease, improving mitochondrial health and reducing disease-related symptoms.

Muscle Wasting and Cachexia: It prevents muscle loss in conditions associated with cancer or chemotherapy, improving muscle mass, energy, and physical performance.

Cognitive Decline: By preserving mitochondrial function, SS-31 supports cognitive health, reducing neuroinflammation and oxidative damage, which can benefit patients with neurodegenerative diseases.

Oxidative Stress and Inflammation: The peptide reduces systemic oxidative stress and inflammation, making it beneficial for conditions linked to mitochondrial dysfunction.
Ischemia-Reperfusion Injury: SS-31 protects against damage in tissues such as the heart and kidneys during ischemia-reperfusion injury, improving recovery and cellular survival.

Dosing: 5 mg = 50 units per injection.

Injections Per Week: 2 injections weekly.

Recommended Cycles: 3 months on (+), 1 month off (-). 3 cycles per year.

Vial Details: 40mg / 4mL

Vial Duration: 4 Weeks

Injection Site: SS31 should be injected subcutaneously, into fatty areas like the stomach, thigh, or upper arm. Rotate injection sites to avoid irritation.

Time of Day: Morning injections are recommended, as it may give you a boost of energy and to take advantage of its energizing effects throughout the day. You can also take it prior to exercise.

Injection Site Reactions: Some users may experience mild redness, itching, or discomfort at the injection site. Rotating the injection site can help minimize these symptoms.

Headache and Dizziness: Headaches and dizziness have been reported, potentially due to increased mitochondrial activity and altered blood flow.

Mild Gastrointestinal Distress: Nausea or stomach discomfort may occur, especially at higher doses, but these symptoms are usually mild and temporary.

Flushing and Fatigue: Users may experience flushing similar to that caused by niacin, along with temporary fatigue as the body adapts to increased mitochondrial function.

Start with a Lower Dose: Gradually increasing the dose can help minimize side effects like nausea and headaches.

Rotate Injection Sites: Avoid injecting in the same area repeatedly to prevent irritation and pain.

Stay Hydrated: Drinking adequate water can help reduce headaches and flushing, as hydration supports optimal mitochondrial function.

Take with Food: If gastrointestinal discomfort occurs, taking SS-31 with food may help alleviate these symptoms.

Consult a Healthcare Provider: Regular monitoring by a healthcare professional is recommended.

1-2 Weeks: Initial improvements in energy levels, reduced muscle soreness, and enhanced endurance are often reported. Increased mitochondrial efficiency can lead to reduced fatigue, especially after physical activity.

4-6 Weeks: Noticeable benefits in cognitive performance and visual function may be observed. Users often report enhanced memory, focus, and low-luminance vision, particularly beneficial for those with age-related macular degeneration.

8-12 Weeks: Significant improvements in muscle mass, reduced oxidative stress, and enhanced cardiovascular health are typical. Consistent use leads to long-term mitochondrial benefits, reduced muscle wasting, and improved quality of life.

Long-term: Continuous use of SS-31 supports mitochondrial health, enhances muscle endurance, and maintains cognitive function, leading to better overall energy levels and reduced disease-related symptoms

SS-31 binds to cardiolipin, preserving the structure of the mitochondrial cristae and maintaining membrane integrity. It prevents mitochondrial swelling and dysfunction, enhances ATP production, and reduces oxidative damage by inhibiting cytochrome c peroxidase activity. It also downregulates the mitochondrial fission protein Fis1, which protects against cellular damage during inflammation, reducing apoptosis (cell death) and preserving energy production. This stabilization improves overall mitochondrial efficiency, supports energy metabolism, and mitigates oxidative stress, especially in tissues prone to mitochondrial dysfunction.