Frequently Asked Questions

Peptides are short chains of amino acids that act as signaling molecules in the body. They help regulate and optimize biological processes such as healing, metabolism, immune function, and cognitive health. Unlike traditional pharmaceuticals, peptides mimic natural processes, making them highly effective with fewer side effects. Peptides are often derived from naturally occurring proteins and can target specific functions in the body without unnecessary systemic effects.

• Improve sleep quality
• Boost cognitive function and mental clarity
• Enhance immunity and reduce inflammation
• Promote muscle recovery and fat loss
• Support skin and hair health
• Increase libido and sexual function
• Strengthen mitochondrial function for increased energy production
• Assist in wound healing and tissue regeneration
• Improve hormonal balance and optimize metabolism

• Injectables – High bioavailability but require needles. 100% bioavailability. 
• Nasal Sprays – Convenient, effective, and easy to use. 50-70% bioavailability.
• Oral (Capsules) – Varies in effectiveness depending on digestion.
• Topicals (Creams/Serums) – Direct absorption for localized effects.

Peptide therapy is suitable for individuals aiming to improve aspects of their health, including weight management, muscle growth, recovery, energy levels, cognitive function, and immune support. Personalized protocols can be developed to meet specific health objectives.

Most peptide therapies show gradual improvement over weeks to months. While some effects are immediate, the best results often come with consistent use over 3-6 months. More information about timeline of benefits for specific peptides are available on the peptides product page, as well as in the information and dosing guide.

The effects of peptides depend on the type of peptide, the duration of use, and individual factors such as your overall health, lifestyle, and treatment goals. Some peptides have long-lasting effects, even after discontinuation, because they help “train” the body to function more optimally. For example, certain peptides can enhance natural hormone production, improve tissue repair, or support metabolic function, leading to sustained benefits even after you stop taking them. Other peptides require consistent use to maintain their effects, similar to how exercise or proper nutrition supports long-term health. If you stop taking these peptides, you may gradually return to your body’s baseline over time, just as you would if you stopped working out.

• We’ve returned to in-house peptide fulfillment to improve speed, reliability, and quality.
• Peptides are now shipped pre-mixed in liquid form—no reconstitution required
• Processing time: Up to 3 business days (most orders ship same or next business day)
• You’ll receive a confirmation email with tracking info once your order ships
• All shipments are packed with insulation and ice packs to maintain temperature stability
• Overnight shipping is used to help preserve potency and ensure fast delivery
• Prefer your peptides in powder form? Just let us know in the “Order Special Instructions” at checkout.

• Processing: Up to 3 business days (often faster)
• Shipping: Overnight delivery
• Most patients receive their peptides within 1–2 days of receiving tracking information

• $60 flat-rate for NY/NJ/CT (Tri-State Area)
• $80 flat-rate for all other U.S. states

• Because we’ve brought fulfillment back in-house, we can typically move much faster than before.
• If you need peptides urgently: Text us or email concierge@extension.health with your order number and request
• While we can’t guarantee same-day shipping, we’ll do our best to prioritize your order when possible
• Most orders already ship same or next business day, but occasional supply delays may still occur
• To avoid gaps in your protocol, please place your next order when you’re down to about 1 week of peptide supply.

If it’s been more than 3 days since receiving your tracking number and your package still hasn’t arrived, reach out to us.
While shipping delays are rare with overnight delivery, we’re happy to help track your order and resolve any issues.

Yes. While we use cold packs to help stabilize peptides in transit, it’s normal for them to arrive melted.
Peptides are formulated to tolerate brief periods out of refrigeration, especially when shipped overnight.

Yes! Peptides tolerate freezing and thawing well.
Simply let your vial thaw at room temperature, then refrigerate it.
Try to avoid repeated freezing and thawing to maintain long-term stability.

• Your order will be ready within 3 business days
• Once you place an order and receive your order number, you can schedule your pick-up appointment
• Appointments are required and must be booked at least 24 hours in advance
• Schedule your pick-up appointment here

• Pick-up appointments are available on Monday, Wednesday, and Friday from 9:30am-4:30pm
• Appointments must be scheduled at least 24 hours in advance to allow our team time to prepare your order

Pick-up is at our West Village office: 160 7th Ave S, New York, NY 10014
Once you arrive, head down the stairs — our front desk team will have your order ready if you scheduled an appointment.

Yes — appointments are required to ensure your peptide is prepared, refrigerated, and that staff are available to assist you.

Scheduling your peptide pick-up ensures that your order is ready, stored properly, and that our team is available to assist you when you arrive. When you book a pick-up appointment, we prepare your order in advance and place it at the front desk for quick and easy handoff. If you're unable to make your scheduled time, we return your order to the refrigerator to maintain potency and safety.

Because we coordinate multiple protocols daily, we’re unable to accommodate unscheduled walk-ins. Scheduled appointments allow us to manage our inventory accurately, avoid delays, and give every patient the time and attention they deserve. Thank you for helping us keep your peptides—and your experience—as seamless and high-quality as possible!

No problem — we’ll hold your order for the rest of the day if you are able to come by before 4:30pm. Just email us at concierge@extension.health to let us know when you'll be coming by.

You can cancel your existing appointment and reschedule for the next available day. Your peptide will be returned to refrigeration and prepped again in time for your new appointment.

There is no extra fee for picking up your peptides in person.

We understand that situations come up and you may need your peptides sooner than expected. While we do our best to accommodate urgent requests, we kindly ask that patients plan ahead whenever possible.

Our standard processing and scheduling timelines are in place to ensure we can manage inventory carefully, maintain peptide quality, and provide reliable, attentive care to every patient.

If you do have a time-sensitive need, please text us or email us at concierge@extension.health and we’ll explore any available options. While we can’t guarantee early fulfillment, we’ll try to assist if we can. Please note that additional rush fees may apply. Thanks for helping us keep the process smooth and respectful for everyone in the EXTENSION Health community!

Currently, peptide therapy is not covered by most insurance plans, and our program is out of pocket only.

We accept a variety of payment methods including credit cards (Visa, MasterCard, American Express), PayPal, and Apple Pay.

Yes, we take the security of our customers' payment information seriously. All transactions are processed securely and we use industry-standard encryption technology to protect your information.

All peptide products purchased from our store are considered medications and are non-refundable and non-returnable. Due to the nature of these products, once an order is placed, it cannot be returned or exchanged.

We are committed to providing high-quality peptides and ensuring your satisfaction with your purchase. If you have any issues or concerns regarding your order, please contact our customer service team, and we will do our best to assist you.

By purchasing from our store, you acknowledge and agree to this policy. If you have any further questions, please feel free to reach out to us. Thank you for understanding.

Yes, when properly sourced and used under medical supervision. Many peptides have been used safely for years in both research and clinical settings. Our team continuously reviews the latest research and adjusts protocols to ensure optimal safety and effectiveness for our patients.

We take quality, safety, and effectiveness seriously. Here is how our peptides stand apart:

• Pharmaceutical-Grade Peptides: Sourced from FDA-inspected, USA-based manufacturers and compounded in a CGMP-certified facility.
• Tested for Purity & Potency: Every batch undergoes mass spectral analysis and RP-HPLC testing, ensuring 99.99% purity.
• Not Salt-Based: Unlike many research-grade or foreign-sourced peptides, our peptides are medical/pharmaceutical grade and are formulated for human use without acetate or salt fillers that can reduce stability and bioavailability. We do not recommend getting peptides from less expensive “research grade” peptide sources online.
• Prescribed by Medical Professionals: Available only to patients under physician supervision. If you are new to peptide therapy, we recommend scheduling a consultation to determine the best options for your health goals.
• Regulatory Compliance & Continuous Monitoring: We stay informed about FDA regulations and evolving guidelines to ensure continued patient access to the safest, most effective peptides available.

Peptides, vary in terms of FDA approval status. Some peptides are FDA-approved for specific medical conditions, while others are available through compounding pharmacies that adhere to strict quality standards. At EXTENSION Health, we source our peptides exclusively from a 503B FDA-registered compounding pharmacy that adheres to strict quality and safety regulations. While these peptides are not considered FDA-approved drugs, they are produced in compliance with cGMP (Current Good Manufacturing Practices) and meet the highest pharmaceutical standards.

FDA approval is not the only measure of a drug’s safety or effectiveness. Many widely used medical treatments began as compounded medications before undergoing the lengthy and expensive FDA approval process. At EXTENSION Health, patient safety is our top priority. That is why we only use the highest quality peptides. Our providers continuously monitor peptide research and regulatory updates, ensuring that all treatments are based on the latest scientific evidence and best clinical practices.

The FDA’s role is to oversee drug safety, manufacturing quality, and public health. However, regulatory restrictions on peptides can also be influenced by pharmaceutical industry influence and lengthy approval processes, rather than concerns about safety or efficacy.

Some key reasons why certain peptides are regulated or restricted include:

• Slow Clinical Trials Process: Many peptides, like BPC-157 and Thymosin Alpha-1, have strong research backing but have not yet completed full FDA trials, which can take years or decades.
• Compounding Pharmacy Regulations: The FDA regulates the production of compounded peptides to ensure sterility and consistency. EXTENSION Health’s peptides come exclusively from a 503B FDA-registered pharmacy, meeting the highest safety standards.
• Pharmaceutical Patents & Monopolization: Companies can patent peptides, making FDA approval for compounded versions difficult.

While FDA scrutiny can create confusion, the peptides used at EXTENSION Health are safe, effective, and carefully sourced from FDA-approved facilities. The restrictions often result from regulatory shifts rather than inherent safety concerns. Many peptides are used successfully in clinical settings globally, and while the U.S. regulatory process can be slow, we hope that increased research and recognition of peptides will lead to wider accessibility in the future.

We are actively monitoring regulations and news about the FDAs position on GLP1s. Currently, our pharmacies are not halting production and GLP1s are available, but that may change. As soon as we have an update, we will send an email to alert you. That said, we are advising patients to stock up just in case. If un-constituted AND stored in a freezer, the shelf life extends well over a year.

The regulatory landscape for peptides is evolving. While some peptides may face increased restrictions, we remain dedicated to providing safe and effective options for our patients.

Our commitment includes:

• Staying ahead of regulatory updates to ensure continued access
• Offering alternative peptides and personalized protocols when availability changes
• Providing ongoing patient education so you can make informed decisions about your health

We encourage patients to explore independent scientific studies and trusted clinical resources. If you would like a list of research studies or regulatory updates, our team is happy to provide additional information upon request. For personalized guidance, schedule a consultation with our expert providers today.

A peptide protocol is a structured and detailed treatment plan designed to optimize the use of peptides for specific health goals. This plan provides:

• Dosing Instructions: Specifies the exact amount of each peptide to use, such as 2 mg per injection.
• Frequency Guidelines: Defines how often the peptide should be administered, such as 5 times per week.
• Cycle Duration: Details the length of time the peptide therapy is followed, such as 3 months on and 1 month off.

Each peptide has unique properties, benefits, and protocols tailored to maximize its effectiveness. These protocols are carefully designed to address diverse health areas, including weight management, muscle growth, enhanced cognition, injury recovery, and long-term vitality. A well-crafted peptide protocol ensures that the therapy is both effective and safe for the patient.

A cycle refers to a structured 4-month period during which peptides are administered according to a personalized plan. Typical cycles involve 3 months of active therapy followed by 1 month off. Our program is built around 3 4 month peptide cycles per year, with most peptides containing a 4 week supply to allow for monthly and full cycle purchases.

• Monthly Orders: Suitable for first-time users or those wanting flexibility to adjust their protocol.
• Full Cycle Purchases: 3 month bundles are discounted at 15% off. Ideal for committed patients, ensuring seamless adherence to the protocol.

• Prevents Resistance – Cycling helps the body remain responsive to peptides, maintaining effectiveness over time.
• Encourages Recovery – Rest periods allow the body to reset and optimize long-term benefits.
• Provides Flexibility – Our program supports three four-month cycles per year (totaling 48 weeks), with built-in flexibility for missed doses or adjustments.

A Multi-Peptide Protocol is a treatment plan that involves using multiple peptides at the same time, following the individual dosing instructions for each peptide. This approach allows for synergistic benefits by combining peptides that target different biological pathways, such as fat loss, muscle growth, recovery, longevity, and cognitive enhancement.

During consultations or follow up appointments, our providers will work with you to create a personalized Multi-Peptide Protocol based on your health goals and ensure that you understand proper dosing, scheduling, and safe administration. If you have questions about which peptides can be taken together, we offer additional resources to guide you in safely and effectively following your protocol.

Dr. Kuo Recommended Protocols are pre-structured treatment plans that include strategically combined peptides commonly used together. These bundles offer a comprehensive approach to addressing multiple health goals.

When you purchase a Dr. Kuo Recommended Protocol, you receive:

• A curated selection of peptides designed for your health concerns
• A comprehensive dosing schedule
• A streamlined approach to achieving optimal results

These protocols offer a holistic and research-backed method for optimizing peptide therapy.

A peptide stack combines multiple peptides into one vial, simplifying dosing and reducing the number of injections. Instead of managing separate schedules, you follow one streamlined protocol while still getting the full benefits of multi-peptide therapy.

Currently, we offer Superhuman Peptide Stacks, with plans to expand to additional peptide stacks in the future.

Our Superhuman Peptide Stacks use advanced science to enhance peptide effectiveness. These stacks improve absorption, extend stability, and optimize results through cutting-edge delivery methods, including:

• Layered FG Peptides – Prevents receptor competition, ensuring peptides work together efficiently.
• Exosome Encapsulation – Uses natural delivery systems to improve absorption and target the right areas.
• PEGylation – Extends peptide activity in the body, reducing dosing frequency while maintaining effectiveness.
• Superhuman Peptide Stacks offer next-level support for longevity, performance, and recovery, delivering maximum therapeutic benefits in the most efficient way possible.

All of our peptides come in 10mL vials, but the amount of liquid solution inside may vary based on the peptide and the prescribed dosage. The mg value on the bottle indicates how much peptide is in the vial, and you can refer to your peptide instruction guide to confirm the amount of bacteriostatic water needed for reconstitution. Most peptides look like they are less than half way full, but that is how they are supposed to look.

Peptides should be stored in the refrigerator to maintain their potency. Protect them from light and heat, and avoid repeated freezing and thawing.

• Powdered Peptides – Shelf life is 2 years in powder form stored in the refrigerator or freezer. Can be left in room temperature for weeks with minimal degradation.
• Liquid Peptides – Once reconstituted, shelf life is 3-6 months if stored properly in the refrigerator, and with good handling, they may remain effective for longer. Can remain stable for up to 7 days without refrigeration, but it is best to keep them consistently cold to maintain their maximum potency.
• Nasal Sprays –  Refrigerate after opening. Shelf life is 3-6 months when stored properly in the fridge. Can last up to 12 months if kept in the freezer before first use.
• Creams – Refrigerate after opening. Shelf life is 6 months refrigerated. Can last up to 12 months if kept in the freezer before first use.

It depends on how long the peptide was left out and whether it was in powder or liquid form. In general, most peptides remain stable at room temperature for several days—often up to 7 days or more—especially if kept away from heat and direct sunlight. If a peptide is left unrefrigerated for an extended period, it may begin to lose some potency, but it typically remains safe to use. The main risk is a gradual decrease in effectiveness rather than safety.

If this happens, just return the peptide to a cool, dry place (ideally the fridge) as soon as possible. If you're ever unsure whether your peptide is still effective or safe to use, feel free to reach out with the details—we’re happy to advise based on your specific situation. For best results, always store your peptides in the refrigerator when not in use.

All our peptide vials are measured to provide approximately a 4-5 week supply when following the standard dosing guidelines. However, some peptides - such as Semaglutide, Tirzepatide, Retatrutide, Melanotan, and Pentosan - are dosed individually based on patient goals and response, meaning vial duration for these peptides vary. More details for each individual peptide vial duration. can be found on the peptide product pages, and information & dosing guide sheets. 

If you adjust your dosing schedule, your vial may last more or less than four weeks, depending on frequency and dose per injection. Minor variations in vial duration are expected and will not impact overall results, as long as the full mg contents are used over the intended period.

A vial lasting slightly more or less than four weeks is normal due to minor variations in dosing, syringe measurements, or human error. This does not affect your overall progress, as peptide therapy is designed to account for slight deviations while ensuring you receive the full mg dosage over time.

If you did not follow the standard dosing protocol, your vial will naturally last a different amount of time. If you believe there was a significant discrepancy with your vial, please contact us, and we can help assess your situation.