KPV (10mg) Injectable
KPV is one of the body’s most powerful natural anti-inflammatory and repair peptides, working at the cellular level to calm inflammation, accelerate tissue regeneration, and restore balance across the gut, skin, and immune systems. It’s ideal for individuals recovering from injury, surgery, or training; managing inflammatory gut or skin conditions; or seeking to reduce chronic inflammation, enhance performance, and support long-term vitality.
VIAL DETAILS
10mg KPV / 4mL / vial. Provides a 4-week supply when following standard dosing protocol of 35 units (0.85mg) injected 3x weekly, or 20 units (0.5mg) 5x weekly.
Keep refrigerated. Use within 1–3 months after mixing for maximum potency. Injection supplies and dosing instructions included.




KPV is safe, gentle, and well-tolerated — making it a versatile option for both therapeutic healing and preventative optimization. Some of its key benefits include:
- Accelerating healing from surgery, training, or injury
- Soothing inflammatory gut conditions like leaky gut, IBS, or IBD
- Calming skin inflammation (eczema, acne, rosacea, psoriasis)
- Supports immune balance and faster recovery from illness or chronic inflammation
- Promote a whole-body wellness and longevity
- Pregnancy or Breastfeeding: Safety has not been established; use is not recommended.
- Known Allergy: Individuals with hypersensitivity to peptide-based therapies should avoid use.
- Severe Autoimmune Disorders: Should be used under supervision for best results and safety for each specific case
KPV is considered very safe and well-tolerated. Mild, short-term effects can occasionally occur, including:
- Mild redness or itching at the injection site
- Temporary fatigue or light nausea
- Minor digestive changes as inflammation improves
These symptoms are typically mild and resolve quickly as your body adjusts.
For safe and informed peptide use, Review the Extension Health Injection Reaction Guide (PDF), which outlines what to expect, how to reduce discomfort, and when to seek medical support when using injectable peptide therapy.
- Inject slowly and let the vial reach room temperature before use.
- Rotate injection sites to prevent irritation.
- Stay hydrated and eat a small snack before injecting.
- Support results with an anti-inflammatory lifestyle: whole-food diet, quality sleep, light movement, and reduced alcohol or processed foods.
KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide derived from the hormone alpha-MSH, which plays a key role in regulating inflammation and immune activity. It works by inhibiting NF-κB, a major signaling pathway that triggers inflammation, and by reducing pro-inflammatory cytokines like TNF-α and IL-6.
At the cellular level, KPV helps restore immune balance and enhances the function of epithelial cells—the protective barrier lining the gut and skin. This dual mechanism makes it effective both systemically and locally, calming inflammation while accelerating tissue repair and regeneration.
First Week:
- Decreased inflammation and mild improvement in joint or gut comfort
- Faster post-exercise recovery and reduced soreness
Weeks 2–4:
- Noticeable improvements in digestion, skin clarity, and tissue healing
- Reduction in pain, redness, or swelling from inflammatory conditions
2–3 Months and Beyond:
- Sustained reduction in inflammation
- Improved gut and skin health
- Enhanced recovery capacity, energy, and long-term resilience
Individual results may vary depending on baseline health, dosage, and concurrent peptide or regenerative protocols.
VIAL DETAILS:
- Amount per vial: 10mg
- Reconstitution volume: 4mL bacteriostatic water
- Concentration: 2.5mg/mL
- Storage: Keep refrigerated after mixing. Avoid exposure to heat or direct sunlight.
- Shelf life: 2 years (powder), 1-3 months after reconstitution (refrigerated), ~3 days at room temperature.
INJECTION SITE & TIMING
Administer injections into subcutaneous fat (such as the stomach, thigh, or arm). More Details: Injection Guide
Injection timing is flexible based on patient preference.
STANDARD DOSE PROTOCOL
20 units (≈0.5mg) 5x weekly
OR
35 units (≈0.83mg) 3x weekly
- Total Weekly Dose ~100 units (≈2.5mg/week), split into the patients' preferred weekly frequency.
- Cycle: Continuous use is safe; optional 1 month off every 3 months is recommended for long-term balance.
- Duration per Vial: ~4 weeks at this dosing protocol.
HIGH DOSE PROTOCOL
40 units (≈1mg) 5x weekly
- Purpose: For accelerated healing or chronic inflammation support.
- Cycle: Typically recommended for 2 weeks–3 months, followed by standard dosing for maintenance.
- Duration per Vial: ~2 weeks at this dosing protocol.
Peptide Reconstitution Guide
This guide is designed to help you reconstitute your powdered peptide vials to prepare them for injection.