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PT-141 (10mg) Injectable

PT-141 naturally enhances sexual arousal and intimacy for both men and women. Unlike traditional medications that simply target blood flow, PT-141 works directly on the brain to activate the pathways that control sexual desire. Whether you’re looking to reignite passion, boost libido, or improve overall sexual satisfaction, PT-141 helps you feel more connected, confident, and in tune with your body.

 

VIAL DETAILS:

10mg PT-141 / 2mL / vial. Provides 5-10 doses depending on personal dose and frequency, with the standard recommendations to be 20-40 units (1-2mg) prior to sexual activity, on an as needed basis.

Keep refrigerated. Use within 1–3 months after mixing for maximum potency. Injection supplies and dosing instructions included. 

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  • Increased Libido: PT-141 stimulates central nervous system pathways tied to sexual desire, helping restore natural interest in intimacy.
  • Improved Sexual Satisfaction: Patients often report stronger arousal, heightened sensitivity, and more fulfilling sexual encounters.
  • Effective in Both Sexes: Shown to improve arousal in women and erectile function in men, making it a versatile option for different needs.
  • Non-Vascular Mechanism: Works through brain receptors rather than blood flow, helpful for patients who do not respond to PDE5 inhibitors like Viagra.
  • On-Demand Use: Designed for use before sexual activity, with flexibility to take only when needed.
  • Uncontrolled Hypertension or Cardiovascular Disease: PT-141 can cause a temporary increase in blood pressure.
  • Pregnant or Breastfeeding Women: Safety has not been established.
  • Severe Liver or Kidney Disease: Use only under medical supervision.
  • Known Allergic Reactions: Contraindicated if you have a hypersensitivity to PT-141 or its components.

PT-141 is generally well-tolerated, but mild and temporary effects may occur. For safe and informed peptide use, Review the Extension Health Injection Reaction Guide (PDF), which outlines possible reactions and when to contact your provider for all peptides.

PT-141 SIDE EFFECTS & CONSIDERATIONS

COMMON:

  • Mild nausea (most common, usually dose-dependent)
  • Flushing or warmth
  • Headache, dizziness, fatigue
  • Temporary increase in blood pressure
  • Injection site irritation

RARE:

  • Rapid heartbeat, fainting, or chest discomfort
  • Severe or persistent nausea/vomiting
  • Allergic reaction (rash, swelling,  shortness of breath)

If you have any questions, please message your healthcare provider through the patient portal or contact us at 646-596-7386.

  1. Start low: Begin with 10 units (1mg) to assess tolerance before increasing to standard dosing of 20 units (2mg).
  2. Take with food: A light meal can reduce nausea.
  3. Stay hydrated: Dehydration may worsen flushing or dizziness.
  4. Avoid alcohol: It may amplify nausea and reduce efficacy.
  5. Monitor blood pressure: Especially if you have hypertension.
  6. Rotate injection sites: To prevent irritation or bruising.

PT-141 binds to and activates melanocortin receptors (MC3R and MC4R) in the brain, which play a key role in regulating sexual arousal and desire. By stimulating these receptors in the hypothalamus, PT-141 promotes an increase in dopamine, a neurotransmitter linked to sexual motivation and pleasure.

Unlike PDE5 inhibitors (Viagra, Cialis), which rely on blood flow, PT-141 acts centrally to enhance sexual interest and responsiveness, making it effective even for individuals who do not respond well to traditional erectile dysfunction or libido-enhancing medications.

  • 30–60 Minutes: Initial effects may begin, often with subtle arousal, warmth, or flushing as the peptide activates brain pathways tied to desire.
  • 1–4 Hours: Peak effects are typically observed, including increased sexual interest, stronger arousal, improved sensitivity, and more reliable erectile response in men. Women often report enhanced responsiveness and satisfaction.
  • Up to 12 Hours: Benefits gradually taper but can last for several hours, sometimes extending into the next day at reduced intensity. Patients often report greater confidence and reduced anxiety during intimacy.
  • Long-Term: With consistent, as-needed use, PT-141 can help restore sexual confidence, improve overall relationship satisfaction, and provide a reliable on-demand option for managing recurrent issues with low libido or arousal.
DOSE PER INJECTION:

1-2mg = 20-40 units per injection.

Recommended to start with 10-20 units (0.5-1mg), assess response, and increase dose to up to 40 units as needed. 

TIME OF DAY:

Inject 30–60 minutes before sexual activity, as needed.

FREQUENCY OF INJECTIONS:

Use only as needed prior to sexual activity. Generally not recommended more than 2x weekly.

INJECTION SITE:

Administer injections into subcutaneous fat (such as the stomach, thigh, or arm). More Details: Injection Guide

VIAL DETAILS:
  • Amount per vial: 10mg
  • Reconstitution volume: 2mL bacteriostatic water
  • Concentration: 5mg/mL
  • Duration: ~5-10 doses, depending on personal use.
STORAGE + SHELF LIFE:
  • Shelf life: 2 years (powder), 3+ months after reconstitution (refrigerated), ~3 days room temp.
  • Storage: Keep refrigerated after mixing when possible. Avoid exposure to heat. Glass is fragile, handle carefully.
Download Instructions

Peptide Reconstitution Guide

This guide is designed to help you reconstitute your powdered peptide vials to prepare them for injection.


Materials Needed

10ml Syringe

10ML syringe

Reconstitution Solution

Reconstitution Solution

Alcohol Wipes

Alcohol Wipes

Peptide Vial(s)

Peptide Vial(s)

Reconstitution Chart

Reconstitution Chart

Download PDF